Bio-Medical Applications of Plasma Devices

The object of this research is to investigate the bacteria inactivation and the mechanism of the cell death (Necrosis and Apoptosis) through the study of plasma-cell interactions by optimizing the bio-medical application plasma suitable to its purpose based on the former research we proposed above. The similarity in the physical property between the cytoplasm and the industrial application plasma provides the alternative way to investigate the ion transport inside the cytoplasm and the mechanism of the interaction with the cell membrane: the plasma simulation of the cytoplasm. It also is possible to investigate the interactions between plasma and living cells, followed by the study of the interactions between the plasma and the cell membrane using the appropriate modeling of the membrane.

Ambient air plasma have been known to kill cancer cells. To enhance selectivity we have used antibody-conjugated nanoparticles. We achieved five times enhancement of melanoma cell death over the case of the plasma alone by using an air plasma with gold nanoparticles bound to anti-FAK antibodies.

We demonstrated that room temperature plasma could be used for tooth whitening. Combining APP helium plasma jet and hydrogen peroxide improved the whitening efficacy by a factor of 3 compared with using hydrogen peroxide alone.

Electron Kinetics in RF Atmospheric-Pressure Microplasmas

The kinetic study of radio-frequency atmospheric-pressure microdischarges had shown three electron groups with three distinct temperatures as well as a flux of energetic electrons (> 5 eV) which can reach the electrodes, deliver energy to the electrodes and tune the surface chemistry in atmospheric-pressure discharges.

AGM-TLM transition and DLM

It had been experimentally known that two modes (AGM and TLM) exist in a DC-driven beam-plasma system. The boundary of the two modes was calculated theoretically and a new mode (double layer mode, DLM) was found.

Instability in a Bounded Beam System

 By the Pierce instability, the uniform electron beam bounded by electrodes becomes unstable and starts to oscillate. Standard routes to chaos (PD and QP) were found in DC and AC driven Pierce systems. And a universal parameter to describe the beam-system was found.

Bifurcation Diagram of a Dielectric Barrier Discharge

A one-dimensional dielectric barrier discharge system driven by a special kind of pulse shows chaotic dynamics. It was found that the route to chaos is different from the conventional standard routes such as PD, QP, and intermittency.

 Dynamics of Vortex Patch with a Point Vortex

 A central vortex patch of uniform vorticity and a point-like intense vortex are merging in a circular cylinder. Whereas the point vortex acts merely as a perturbation to generate the surface waves in the linear limit, it acts like a ¡°mixing¡± agent in this nonlinear limit (G = 0.31).